Generalized Eruptive Histiocytosis in a Patient with Chronic Myelomonocytic Leukemia
ثبت نشده
چکیده
An 80-year-old man visited our department with asymptomatic skin lesions that had appeared 2 months earlier. The patient stated that he was not receiving any regular treatments and had not been administered new drugs; he reported no fever or other symptoms and did not recall having been bitten or stung. Physical examination revealed erythematous papules on the upper part of the torso; the papules measured approximately 3 mm in diameter and were firm with a depressed center (Figs. 1 and 2). Some of the papules had coalesced to form plaques. The mucosa, palms, and soles were not affected. A skin biopsy revealed a dense infiltrate in the papillary and middle dermis, consisting mainly of histiocytes, some of
منابع مشابه
Generalized eruptive histiocytosis: A case report
The histiocytoses are a group of proliferative disorders of themonocyte-macrophage lineage that are neoplastic or reactive innature. Based on immunophenotyping and electron microscopy,two main groups have been recognized namely 1) Langerhanscell histiocytosis (LCH) and 2) non- Langerhans cell histiocytosis(non-LCH). In this study, a fairly rare disease of the non-LCHgroup, generalized eruptive ...
متن کاملGeneralized eruptive histiocytosis in a patient with chronic myelomonocytic leukemia.
An 80-year-old man visited our department with asymptomatic skin lesions that had appeared 2 months earlier. The patient stated that he was not receiving any regular treatments and had not been administered new drugs; he reported no fever or other symptoms and did not recall having been bitten or stung. Physical examination revealed erythematous papules on the upper part of the torso; the papul...
متن کاملSubacute dermal monocytic sarcoma: report of a case of monocytic leukemia with initial dermal presentation
Monocytic sarcoma is a neoplasm of immature monocytes involving any extramedullary site such as skin. The definite diagnosis is important for adequate therapy, which is often delayed becauseof misdiagnosis. We report a 51-Year-old diabetic woman who presented with several erythematous itchy papules and plaques on her s...
متن کاملA Rare Case of Acute Myeloid Leukemia with Translocation (3:3) Presenting with Features of Chronic Myelomonocytic Leukemia
Background: Acute Myeloid Leukemia (AML) with translocation (3,3) is a form of AML that may present de novo or may arise from a previous myelodysplastic syndrome. It is often associated with normal or elevated peripheral blood platelet count and increased bone marrow megakaryocytes with associated multi lineage dysplasia. A subset of patients present with hepatosplenomegaly while a few cases h...
متن کاملDetermination of Monosomy 7 among In Vitro Generated CD1a Positive Cells in Patients with Juvenile Myelomonocytic Leukemia
Objective: To study whether the generated CD1a positive cells belong to the leukemic cells among patients with juvenile myelomonocytic leukemia. Materials and Methods: We used mononuclear cells from 3 patients with juvenile myelomonocytic leukemia, from which two had monosomy 7. The mononuclear cells from these patients were cultured in RPMI/10%FCS without adding exogeneous growth factors fo...
متن کامل